IJCEM Copyright © 2008-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711
Int J Clin Exp Med 2010;3(3):341-346

Original Article
A novel colonic anastomosis technique involving fixed polyglycolic acid mesh

Erhan Aysan, Hasan Bektas, Feyzullah Ersoz, Serkan Sari, Arslan Kaygusuz

Istanbul Educational and Research Hospital, Department of General Surgery, Emirhan Cad. No: 3 Besiktas - Istanbul, Post code:
80700, Turkey.

Received April 18, 2010, accepted October 20, 2010, available online October 24, 2010

Abstract: Background: Polyglycolic acid mesh (PAM) reinforcement of colonic anastomoses were evaluated. Methods: Twenty female
albino rabbits were divided into two groups. Each rabbit underwent segmental colonic resection with single-layer anastomosis. In one
group of rabbits, PAM of length equal to the circumference of the anastomosis was applied. Rabbits were sacrificed on postoperative
day 10 and peritoneal adhesions, anastomosis burst pressure, and anastomosis histopathological characteristics were evaluated.
Results: The average burst pressure for the control and PAM groups was 149±15.95 mmHg and 224±124.5 mmHg, respectively
(p=0.578). All control anastomoses burst, whereas only five (50%) PAM anastomoses burst (p<0.03). There was no anastomotic
leakage in the control group, whereas three PAM group anastomoses leaked (p=0.210). The collagen fiber density and amount of
neovascularization were lower in the PAM than the control group (p=0.001 and p=0.002, respectively). The average peritoneal adhesion
value was 1.6±0.51 in the control group and 2.9±0.31 in the PAM group (p<0.0001). Conclusion: The new fixed PAM-reinforced
anastomosis technique resulted in an increased risk of anastomosis leakage and peritoneal adhesion, but also higher in non-burst
anastomoses. (IJCEM1004002).

Key words: Anastomosis, polyglycolic acid, colon, mesh, novel, technique

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