Original Article The prevalence and risk factors of decreased bone mineral density in firstly diagnosed ulcerative colitis patients in the eastern region of turkey
Levent Ediz, Ahmet Cumhur Dülger, Murat Toprak, Mehmet Fethi Ceylan, Özgür Kemik
Yuzuncu Yil University, Medical Faculty, Physical Medicine And Rehabilitation Department, Van, Turkey; Yuzuncu Yil University, Medical Faculty, Gastroenterology Department, Van, Turkey; Yuzuncu Yil University, Medical Faculty, Orthopaedics Department, Van, Turkey; Yuzuncu Yil University, Medical Faculty, General Surgery Department, Van, Turkey.
Received February 26, 2011; accepted March 31, 2011; Epub April 3, 2010; published may 15, 2011
Abstract: The prevalance of osteoporosis or osteopenia in Turkish population with ulcerative colitis (UC) at the diagnosis time has not been evaluated so far. Therefore we aimed to determine the prevelance and risk factors of decreased bone mineral density (BMD) in UC patients at the diagnosis time in Turkey. We retrospectively evaluated dexa results, demographic and clinical characteristics, and some biochemical markers of bone turnover of the UC patients at the diagnosis time between June 2005 and February 2010 from the gastroenterology clinic records of the university hospital. The study population consisted of firstly diagnosed 63 UC patients (male: female = 27: 36; mean age 41.8 years). 38.1% at lumbar spine and 44.4% at femoral neck of the Turkish UC patients patients had low BMD at the diagnosis time. The occurrence of osteoporosis among Turkish UC patients at the diagnosis time were 8% at lumbar spine and 11% at femoral neck. 30.1% at lumbar spine and 33.3% at femoral neck of the patients had osteopenia at the diagnosis time. Pearson’s coefficient of correlation showed significant correlations between low BMD and pancolitis (p<0.01), age, menopause, and symptom duration before the diagnosis (p<0.05).In conclusion, the prevelance of low bone density at the diagnosis time in Turkish UC patients is in accordance with Western and Eastern societies. Pancolitis, age, duration of symptoms, and menopause are predictive factors for low bone density in these patients. (IJCEM1102009).
Address all correspondence to: Levent Ediz, MD, PhD Yuzuncu Yil University Medical Faculty Physical Medicine and Rehabilitation Department YYU Arastirma Hastanesi, 65000, Van, Turkey. E-mail: email@example.com