IJCEM Copyright © 2008-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711
Int J Clin Exp Med 2013;6(4):298-306

Case Report
Primary cervical and uterine corpus lymphoma; a case report and literature review

Antonios Anagnostopoulos, Niki Mouzakiti, Stuart Ruthven, Jonathan Herod, Michail Kotsyfakis

Liverpool Women’s Hospital, Liverpool, United Kingdom; Broomfield Hospital, Chelmsford, Essex, United Kingdom; Royal Liverpool
University Hospital, Liverpool, United Kingdom; Biology Center of the Academy of Sciences of Czech Republic, Ceske Budejovice,
Czech Republic

Received January 20, 2013; Accepted March 25, 2013; Epub April 12, 2013; Published April 30, 2013

Abstract: Primary lymphoma of the uterine corpus and cervix is rare. We present a case of primary non-Hodgkin follicular lymphoma
isolated to uterine corpus and parametria with focal spread to ovaries and fallopian tubes, incidentally found on the background of
endometrial malignancy. A summary of the published cases focusing on the presentation and prognosis as well as a review of current
management are discussed. The rising incidence of extra-nodal lymphoma and recent changes in classification and therapeutic
approach, require clinical vigilance. In the absence of prospective studies assessing the value of the available therapeutic options, data
from retrospective series and scattered case reports are presented in this review. (IJCEM1303016).

Keywords: Non-Hodgkin’s lymphoma, extra-nodal lymphoma, uterine/cervical lymphoma

Address correspondence to: Dr. Michail Kotsyfakis, Biology Centre, Academy of Sciences of the Czech Republic, Branisovska 31,
37005 Ceske Budejovice, Czech Republic. Phone: (+420) 387775492; Fax: (+420) 385310388; E-mail: kotsyfakis@paru.cas.cz