IJCEM Copyright © 2008-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711
Int J Clin Exp Med 2013;6(5):358-366

Original Article
Associated influence of hypertension and heart rate greater than 80 beats per
minute on mortality rate in patients with anterior wall STEMI

Goran Davidovic, Violeta Iric-Cupic, Srdjan Milanov

Clinic of Cardiology, Clinical Center Kragujevac, Kragujevac, Serbia; Faculty of medical sciences, University in Kragujevac, Kragujevac,
Serbia

Received April 6, 2013; Accepted May 3, 2013; Epub May 22, 2013; Published June 1, 2013

Abstract: Acute myocardial infarction as a form of coronary heart disease is characterized by permanent damage/loss of anatomical
and functional cardiac tissue. Diagnosis of STEMI includes data on anginal pain and persistent ST-segment elavation. According to the
numerous epidemiological studies, arterial blood pressure and heart rate are offten increased especially during the first hours of pain
due to domination of sympathetic response. We wanted to investigate the associated influence of heart rate greater than 80 beats per
minute and hypertension on the mortality in patients with anterior wall STEMI. Research included 140 patients treated in Coronary Unit,
Clinical Center Kragujevac form January 2001 to June 2006. Heart rate was calculated as the mean value of baseline and heart rate in
the first 30 minutes after admission, recorded on monitor and electrocardiogram. Data for history of hypertension were collected and
blood pressure levels were measured in a lying position after 5 minutes of rest, and classified according to the VII JNC
recommendations as confirmation of hypertension. Collected data were analyzed in SPSS 13.0 for Windows. Heart rate greater than 80
bpm influences the hospital mortality. Systolic blood pressure levels were higher in the survivors, while for the diastolic there was no
difference. History of hypertension was singled out as a significant predictor of mortality without difference between the respondents
with heart rate greater and lower than 80 bpm in the survivors and fatal. Increased heart rate and hypertension at admission are
significant predictors of mortality in patients with anterior wall STEMI. (IJCEM1304005).

Keywords: Heart rate greater than 80 bpm, hypertension, STEMI

Address correspondence to: Dr. Goran Davidovic, Kopaonicka 5/II, P. Box 22, 34000 Kragujevac, Serbia. Tel: +381 64 67 91 200;
E-mail: medicusbg@yahoo.com; akreditacija@medf.kg.ac.rs