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| IJCEM Copyright © 2008-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711 |
Int J Clin Exp Med 2013;6(9):757-765
Original Article
Personal hair dyes use and risk of glioma: a meta-analysis
Chuan Shao, Zhen-Yu Qi, Guo-Zhen Hui, Zhong Wang
Department of Neurosurgery, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, 215006, Jiangsu, China
Received August 5, 2013; Accepted September 12, 2013; Epub September 25, 2013; Published September 30, 2013
Abstract: Background and Objective: Use of hair dyes for glioma risk has been investigated in numerous epidemiological studies, but
the evidence is inconsistent. Therefore, a meta-analysis was performed to estimate the association between hair dyes use and glioma
risk. Methods: We searched PubMed and EMBASE databases without any limitations, covering all papers published by the end of
March 8, 2013. Cohort and case-control studies reporting relative risk estimates (RRs) with corresponding 95% confidence intervals
(CIs) (or data to calculate them) on this issue were included. Random effects models were used to calculate the pooled RRs and
corresponding 95% CIs. Results: Four case-control and two cohort studies were included in this meta-analysis. The summary RRs
and 95 % CIs for ever users of any hair dyes were 1.132 (0.887-1.446) for all studies, 1.291 (0.938-1.777) for case-control studies, and
0.903 (0.774-1.054) for cohort studies. In the subgroup analysis by geographic regions and sex, the similar results were detected. No
significant associations were also observed among the studies which reported data involving permanent hair dye use and duration of
any hair dye use. Conclusion: In summary, the results of our study demonstrated that hair dyes use is not associated with risk of
glioma. (IJCEM1308007).
Keywords: Glioma, hair dyes, risk factor, meta-analysis
Address correspondence to: Dr. Zhen-Yu Qi, Department of Neurosurgery, The First Affiliated Hospital of Soochow University, 188
Shizi Road, Suzhou, 215006, Jiangsu, China. Tel: 86-512-68161750; E-mail: qizhenyu@suda.edu.cn
Original Article
Personal hair dyes use and risk of glioma: a meta-analysis
Chuan Shao, Zhen-Yu Qi, Guo-Zhen Hui, Zhong Wang
Department of Neurosurgery, The First Affiliated Hospital of Soochow University, 188 Shizi Road, Suzhou, 215006, Jiangsu, China
Received August 5, 2013; Accepted September 12, 2013; Epub September 25, 2013; Published September 30, 2013
Abstract: Background and Objective: Use of hair dyes for glioma risk has been investigated in numerous epidemiological studies, but
the evidence is inconsistent. Therefore, a meta-analysis was performed to estimate the association between hair dyes use and glioma
risk. Methods: We searched PubMed and EMBASE databases without any limitations, covering all papers published by the end of
March 8, 2013. Cohort and case-control studies reporting relative risk estimates (RRs) with corresponding 95% confidence intervals
(CIs) (or data to calculate them) on this issue were included. Random effects models were used to calculate the pooled RRs and
corresponding 95% CIs. Results: Four case-control and two cohort studies were included in this meta-analysis. The summary RRs
and 95 % CIs for ever users of any hair dyes were 1.132 (0.887-1.446) for all studies, 1.291 (0.938-1.777) for case-control studies, and
0.903 (0.774-1.054) for cohort studies. In the subgroup analysis by geographic regions and sex, the similar results were detected. No
significant associations were also observed among the studies which reported data involving permanent hair dye use and duration of
any hair dye use. Conclusion: In summary, the results of our study demonstrated that hair dyes use is not associated with risk of
glioma. (IJCEM1308007).
Keywords: Glioma, hair dyes, risk factor, meta-analysis
Address correspondence to: Dr. Zhen-Yu Qi, Department of Neurosurgery, The First Affiliated Hospital of Soochow University, 188
Shizi Road, Suzhou, 215006, Jiangsu, China. Tel: 86-512-68161750; E-mail: qizhenyu@suda.edu.cn
